IPM - Institute for Research in Fundamental Sciences

Bioinformatics Research Group @ IPM

 
 
 
Bioinformatics Research Group @ IPM
     
 

 

 

 

Mehdi Sadeghi 

 

 

 

National Institute of Genetic Engineering and Biotechnology, Tehran-Karaj Highway, Tehran, P.O. Box 14155-6343, Iran

 

sadeghi@nigeb.ac.ir

m-sadeghi@ibb.ut.ac.ir

 

 

 

 

Educational background

1991: Bachelor of Science in Cellular and Molecular Biology (University of Tehran).

 

1993: Master of Science in Biophysics (University of Tehran)

 

2001: PhD of Biophysics (University of Tehran).

Thesis: "Prediction of Protein Surface Accessibility using Information Theory".

 

 

 

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Selected Publications:

1-     Leila Pirhaji , Mehdi Kargar , Armita Shearic, Hadi Poormohammadi, Mehdi Sadeghi, Hamid Pezeshk, Changiz Eslahchi (2008) The performances of the chi-square test and complexity measures for signal recognition in biological sequences, Journal of Theoretical Biology, IN press

 

 

2-     Sayed-Amir Marashi, Mehdi Kargar, Ali Katanforoush, Hassan Abolhassani and Mehdi Sadeghi (2007) Evolution of ‘Ligand-Diffusion Chreods’ on Protein-Surface Models:A Genetic Algorithm Study, Chemistry and Biodiversity, vol 4, 2766-2771

 

3-     Shahriar Arab, Farzad Didehvar, Changiz Eslahchi, Mehdi Sadeghi (2007) Helix segment assignment in proteins using fuzzy logic , IRANIAN JOURNAL of BIOTECHNOLOGY, Vol. 5, 93-99

 

4-     Roghayeh Zarei, Shahriar Arab and Mehdi Sadeghi (2007) A Method for Protein Accessibility Prediction based on Residue Types and Conformational States, Computational Biology and Chemistry, Vol. 31, 384–388

 

5-     Fereshteh Chitsazian, Betsabeh Khoramian Tusi, Elahe Elahi,‡ Heidar Amini Saroei, Mohammad H. Sanati, Shahin Yazdani, Mohammad Pakravan, Navid Nilforooshan,_ Yadollah Eslami, Mohammad Ali Zare Mehrjerdi, Reza Zareei, Mahmood Jabbarvand, Ali Abdolahi, Ali R. Lasheyee, Arash Etemadi, Behnaz Bayat, Mehdi Sadeghi, Mohammad M. Banoei, Behnam Ghafarzadeh, Mohammad R. Rohani, Akram Rismanchian, Yvonne Thorstenson, and Mansoor Sarfarazi (2007) "CYP1B1 Mutation Profile of Iranian Primary Congenital Glaucoma Patients and Associated Haplotypes". Journal of Molecular Diagnostics, Vol. 9, No. 3, 382-392

 

6-     Khosrow Khalifeh, Bijan Ranjbar, Khosro Khajeh, Hossein Naderi-Manesh, Mehdi Sadeghi and Sara Gharavi (2007) "A stopped-flow fluorescence study of the native and modified lysozyme", Biologia, volum 62,No.3: 258—264

 

7-     Narges Kh. Tafreshi, Saman Hosseinkhani, Majid Sadeghizadeh, Mehdi Sadeghi, Bijan Ranjbar and Hossein Naderi-Manesh (2007) "The Influence of Insertion of a Critical Residue (Arg356) in Structure and Bioluminescence Spectra of Firefly Luciferase", THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 282, NO. 12, pp. 8641–8647,

 

8-      Z Moosavi-Movahedi, S Safarian, M Zahedi, M Sadeghi, AA Saboury, J Chamani, H Bahrami, A Ashraf-Modarres and AA Moosavi-Movahedi (2006) "Calorimetric and Binding    Dissections of HAS Upon Interaction with Bilirubin", The Protein Journal, 25(3), 193-201

 

9-     Moosavi-Movahedi AA, Gharanfoli M, Jalili S, Ahmad F, Chamani J, Hakimelahi GH, Sadeghi M, Amani M, Saboury AA. (2006) "The correlation of Rnase A enzymatic activity with the changes in the distance between Nd2-His12 and Nd1-His119 upon addition of stabilizing and destabilizing salts", The Protein Journal, 25(2), 117 – 125

 

10-  Marashi SA, Eslahchi C, Pezeshk H, Sadeghi M. (2006) "Impact of RNA structure on the prediction of donor and acceptor splice sites" BMC Bioinformatics. 13;7(1):297

 

11-  Maryam Monsef Shokri , Khosro Khajeh , Jahan Alikhajeh , Ahmad Asoodeh ,  Bijan Ranjbar , Saman Hosseinkhani , Mehdi Sadeghi (2006) " Comparison of the molten globule states of thermophilic and mesophilic α-amylases ", Biophysical Chemistry, Volume 122, Issue 1:58-65

 

12-  Sayed-Amir Marashi , Hani Goodarzi , Mehdi Sadeghi , Changiz Eslahchi ,Hamid Pezeshk (2006) "Importance of RNA secondary structure information for yeast donor and acceptor splice site predictions by neural networks" Computational Biology and Chemistry, 30: 50-57

 

13-  Leila Hassani , Bijan Ranjbar , Khosro Khajeh , Hossein Naderi-Manesh , Mehdi Naderi-Manesh, Mehdi Sadeghi (2006) "Horseradish peroxidase thermostabilization:The combinatorial effects of the surface modification and the polyols" Enzyme and Microbial Technology,  38: 118-125

 

14-  Khosro Khajeh, Maryam Monsef Shokri , S. Mohsen Asghari , Fatemeh Moradian, Atiah Ghasemi, Mehdi Sadeghi, Bijan Ranjbar, Saman Hosseinkhani, Sara Gharavi, Hossein Naderi-Manesh (2006) "Acidic and proteolytic digestion of α-amylases from Bacillus licheniformis and Bacillus amyloliquefaciens:Stability and flexibility analysis" Enzyme and Microbial Technology, 38: 422-428

 

15-  Mehdi Sadeghi, Hossein Naderi-Manesh, mahbobeh Zarrabi and Bijan Ranjbar (2006)   "Effective factors in thermostability of thermophilic proteins", Biophysical Chemistry, 119: 256-270

 

16-  Ali Akbar Saboury, Malihe Sadat Atri, Mohammad Hossein Sanati and Mehdi Sadeghi (2005) "Application of a simple calorimetric data analysis on the binding study of calcium ions by human growth hormone" Journal of Thermal analysis and calorimetry, 83:175 – 179

 

17-  Saboury AA, Atri MS, Sanati MH, Moosavi-Movahedi AA, Hakimelahi GH, Sadeghi M (2006) "A thermodynamic study on the interaction between magnesium ion and human growth hormone."Biopolymers, 81:120-126

 

18-  Saber Zahri, Mohammad Reza Zamani*, Mostafa Motallebi, Mehdi Sadeghi (2005)   “Cloning and characterization of cbhII gene from Trichoderma parceramosum and its expression in Pichia pastoris” Iranian Journal of Biotechnology, Vol. 3, No. 4, 204-215

 

19-  M. S. Atri, A. A. Saboury, M. Rezaei-Tavirani, M. H. Sanati, A. A. Moosavi-Movahedi, M. Sadeghi, H. Mansuri-Torshizi, M. Khodabandeh (2005) "Binding Properties and Conformational Change of Human Growth Hormone upon Interaction with Fe+3 ", Thermochimica Acta. 438: 178-183

 

20-  Mehdi Sadeghi, Sahar Parto, Shahriar Arab and Bijan Ranjbar (2005) "Prediction of protein secondary structure based on residue pair types and    conformational states using dynamic programming algorithm", FEBS Letters, 579: 3397-3400

 

21-  Seyed-omid ranaei, Gholam-Hossein Riazi, Mehdi Sadeghi and et al (2004) "Modification of substrate inhibition of synaptosomal acetylcholinesterase by cardiotoxin", J. Biochem. Mol. Biol., 37: 330-338

 

22-  Davood Ajloo, Ali akbar Moosavi Movahedi, mehdi Sadeghi and Housain Gharibi (2002)"Comparative structural and functional studies of avian and mammalian hemoglobin", Acta Biochemica Polonica, 49: 459-470

 

23-  Hossein Naderi-Manesh, Mehdi Sadeghi, Shahriar Arab and Ali Akbar Moosavi movahedi (2001) "Prediction of protein surface accessibility with information theory", PROTEINS, 42: 452-459

 

 

 

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